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Henry F. "Chip" Chambers, M.D.
Professor of Medicine
Chief, Division of Infectious Diseases, SFGH
Director, UCSF Infectious Diseases Fellowship Training Program
hchambers@medsfgh.ucsf.edu

Mailing Address:
Division of Infectious Diseases
San Francisco General Hospital
1001 Potrero Avenue Box 0811
San Francisco, CA 94110

Office Location:
Room 3400, SFGH

Research Interests:
Antimicrobial resistance; genetics, molecular basis, and epidemiology of methicillin-resistant Stahylococcus aureus; staphylococcal infections, tuberculosis

Select Publications:

Diep BA, Stone GG,  Basuino L, Christopher JG, Miller A, des Etages SA, Jones A, Palazzolo-Ballance AM, Perdreau-Remington F, Sensabaugh GF, DeLeo FR, Chambers HF.  The ACME and SCCmec linkage of virulence with resistance in the USA300 clone of community methicillin resistant Staphylococcus aureus.   J Infect Dis, 197:1523-30, 2008. 

Liu C, Graber CJ,  Karr M,  Diep BA, Basuino L,  Schwartz BS, Enright MC, O'Hanlon SJ, Thomas JC,  Perdreau-Remington F,  Gordon S,  Gunthorpe H, Jacobs R,  Jensen P,  Leoung G, Rumack J, Chambers HF.   A population-based study of the incidence and molecular epidemiology of methicillin-resistant Staphylococcus aureus Disease in San Francisco, 2004-2005.  Clin Infect Dis, 46:1637-46 2008. 

Banerjee R, Gretes M, Basuino L, Strynadka, Chambers HF.  In vitro selection and characterization of ceftobiprole-resistant methicillin resistant Staphylococcus aureus (MRSA).  Antimicrob Agents Chemother, 52:2089-96, 2008.

Hersh AL, Chambers HF, Maselli JH, Gonzales R.  National trends in ambulatory visits and antibiotic prescribing for skin and soft-tissue infections.  Arch Intern Med, 168:1585-9, 2008.  
 
Chambers HF, Basuino L, Diep B, Steenbergen J, Zhang S, Tattevin P, Alder J. Relationship between susceptibility to daptomycin in vitro and activity in vivo in the rabbit model of aortic valve endocarditis. Antimicrob Agents Chemother 53:1463-7, 2009.
 
Li M, Diep B, Villaruz, A, Bruaghton, Jiang X, DeLeo FR, Chambers HF, Lu Y, Otto M. Evolution of virulence in epidemic community-associated methicillin-resistant Staphylococcus aureus. Proc Natl Acad Sci U S A.106:5883-8, 2009.

Chambers HF, Deleo FR. Waves of resistance: Staphylococcus aureus in the antibiotic era. Nat Rev Microbiol. 7:629-41, 2009.

Diep BA, Chan L, Tattevin P, Kajikawa O, Martin TR, Basuino L, Mai TT, Marbach H, Braughton KR, Whitney AR, Gardner DJ, Fan X, Tseng CW, Liu GY, Badiou C, Etienne J, Lina G, Matthay MA, DeLeo FR, Chambers HF. Polymorphonuclear leukocytes mediate Staphylococcus aureus Panton-Valentine leukocidin-induced lung inflammation and injury. Proc Natl Acad Sci U S A. 107:5587-92, 2010.

Education and Training:

B.S., Centre College, Danville, KY, 1973

M.D., Vanderbilt University, Nashville, TN, 1977

Internal Medicine Residency, University of California, San Francisco 1977-1980

Chief Residency, Medicine, San Francisco General Hospital/ University of California, 1980-1981

Infectious Disease Fellowship, University of California, San Francisco, 1981-1985


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