Richard Locksley , M.D.
Sandler Distinguished Professor of Medicine and Microbiology/Immunology
Investigator, Howard Hughes Medical Institute
Director, Sandler Asthma Basic Research Center
locksley@medicine.ucsf.edu

Mailing Address:
University of California, San Francisco
Division of Infectious Diseases
513 Parnassus Avenue, Box 0795
San Francisco, CA 94143

Office Location:
Medical Sciences Building, S-1032B

Research Interests:
Cytokine expression and regulation in immune cells in response to infectious and inflammatory agents.

Select Publications:

Locksley RM, NJ Killeen, MJ Lenardo. 2001. The TNF and TNF receptor superfamilies:  integrating mammalian biology. Cell. 104:487-501.

Shinkai K, M Mohrs, RM Locksley. 2002. Helper T cells regulate type 2 immunity in vivo. Nature. 420:825-829.

Voehringer D, K Shinkai, RM Locksley. 2004. Type 2 immunity reflects orchestrated recruitment of cells committed to IL-4 production. Immunity. 20:267-277.

Xu M, ZE Wang, RM Locksley. 2004. Innate Immune responses in peptidoglycan-recognition-protein-L-deficient mice.  Mol Cell Biol. 24:7949-7957.

Voehringer D, DB Rosen, LL Lanier, RM Locksley. 2004. CD200R family members represent novel DAP12-associated activating receptors on basophils and mast cells. J Biol Chem. 279:54117-54123.

Education and Training:

M.D., University of Rochester, 1976

Residency, Chief Residency, University of California, San Francisco, 1976-1980

ID Fellowship, University of Washington, Seattle, 1980-1983

Relevant Links:

http://www.ucsf.edu/immuno/faculty/locksley.html

http://www.ucsf.edu/bms/immunology.html

http://cancer.ucsf.edu/people/locksley_richard.php

http://www.hhmi.org/research/investigators/locksley_bio.html

Dr. Locksley is also a recipient of the 2005 Excellence in Direct Teaching Award.